Mechanical signaling in the heart via abLIM-1 phosphorylation

Research Funding Committee - Loyola University Chicago
Award Type: New Investigator Pilot Project
Role: PI
Costs: $50,000

Non-muscle myosin 2 can incorporate into established filaments in cells without an assembly competence domain

Wu K, Patel H, Wu H, Quintanilla MA, Bennet MA, Sala S, Beach JR^✉
Submitted (2024)
DOI | bioRχiv

Smooth Muscle Myosin 2 Filaments Dynamically Assemble and Stabilize During Induced Contractility

Bennet MA, Demeulenaere SG, Wu H, Patel H, Sala S, Longtine ER, Oakes PW, Beach JR^✉
Submitted (2022)
DOI | bioRχiv

Principles and Regulation of Mechanosensing

Sala S*, Caillier A*, Oakes PW^✉
J Cell Sci 137(18):jcs261338 (2024)
PDF | DOI | PMID: 39297391

Machine learning interpretable models of cell mechanics from protein images

Schmitt MS*, Colen J*, Sala S, Devany J, Seetharaman S, Caillier A, Gardel ML^✉, Oakes PW^✉, Vitelli V^✉
Cell 187(2):481-494 (2024)
PDF | DOI | arΧiv | Twitter thread | PMID: 38194965

Repair of Noise-induced Damage to Stereocilia F-actin Cores is Facilitated by XIRP2 and its Novel Mechanosensor Domain

Wagner EL, Im J-S, Sala S, Nakahata MI, Imbery TE, Li S, Chen D, Nimchuk K, Noy Y, Archer DW, Xu W, Hashisaki G, Avraham KB, Oakes PW, Shin J-S^✉
eLife 12:e72681 (2023)
PDF | DOI | bioRχiv | PMID: 37294664

LIM domain proteins

Sala S, Oakes PW^✉
Curr Biol 33(9):R339-341 (2023)
PDF | DOI | PMID: 37160086

Zyxin is all you need: machine learning adherent cell mechanics

Schmitt MS*, Colen J*, Sala S, Devany J, Seetharaman S, Gardel ML^✉, Oakes PW^✉, Vitelli V^✉
Submitted (2023)
DOI | arΧiv | Twitter thread | PMID: 36911285

Quantifying Strain-Sensing Protein Recruitment During Stress Fiber Repair

Seetharaman S*, Sala S*, Gardel ML^✉, Oakes PW^✉
Meth Mol Biol, 2600:169-182 (2023)
PDF | DOI | PMID: 36587097

Stress fiber strain recognition by the LIM protein testin is cryptic and mediated by RhoA

Sala S, Oakes PW^✉
Mol Biol Cell, 32(18):1758-1771 (2021)
PDF | DOI | bioRxiv | Twitter thread | PMID: 34038160

An emerging link between LIM domain proteins and nuclear receptors

Sala S, Ampe C^✉
Cell Mol Life Sci, 75(11):1959-1971 (2018)
DOI | PMID: 29428964

The PET and LIM1-2 domains of testin contribute to intramolecular and homodimeric interactions

Sala S, Catillon M, Hadzic E, Schaffner-Reckinger E, Van Troys M, Ampe C^✉
PLoS One, 12(5):e0177879 (2017)
DOI | PMID: 28542564

Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations

Sala S, Van Troys M, Medves S, Catillon M, Timmerman E, Staes A, Schaffner-Reckinger E, Gevaert K, Ampe C^✉
J Proteome Res, 16(5):2054-2071 (2017)
DOI | PMID: 28378594